PUBLICATIONS
2021
Attention-Deficit Hyperactivity Disorder and Obesity – A National Study of 1.1 Million Israeli Adolescents
Pinhas Hamiel O, Bardugo A, Reichman B, Derazne E, Landau Z, Tokalty-Latzer I, Lerner-Geva L, Rotschield J, Tzur D, Ben-Zvi D, Afek A, Twig G.
Journal of Clinical Endocrinology and Metabolism. Accepted (2021)
Sleeve gastrectomy suppresses hepatic glucose production and increases hepatic insulin clearance independent of weight-loss
Ben-Haroush Schyr R#, Al-Kurd A, MoalemB, Permyakova A, Israeli H, Bardugo A, Hefetz L, Bergel M, Haran A, Azar S, Magenheim I, Tam J, Grinbaum R, Ben-Zvi D#.
Diabetes. . Oct; 70(10) 2289-98 (2021)
Bariatric Surgery Affects Plasma Levels of Alanine Aminotransferase Independent of Weight Loss: A Registry-Based Study
Journal of Clinical Medicine. 10(12), 2724 (2021)
Structure reveals the activation mechanism for MC4 receptor to initiate satiation signaling
Hadar Israeli*, Oksana Degtjarik*, Fabrizio Fierro, Vidicha Chunilal, Amandeep Kaur Gill, Nicolas J Roth, Joaquin Botta, Vadivel Prabahar, Yoav Peleg, Li F Chan, Danny Ben-Zvi#, Peter McCormick#, Masha Y Niv#, Moran Shalev-Benami#.
Science, May 21 372(6544) 808-814 (2021)
Sleeve Gastrectomy is associated with a greater reduction in Plasma Liver Enzymes than Bypass Surgeries: A Registry Based Two-Year Followup Study
Journal of Clinical Medicine. 10(5) 1144 (2021)
a-Synuclein-induced Kv4 channelopathy in mouse vagal motoneurons drives nonmotor parkinsonian symptoms
Weih-Hua Chiu, Lora Kovacheva, Ruth E Musgrove, Hadar Arien-Zakay, James B Koprich, Jonathan M Brotchie, Rami Yaka, Danny Ben-Zvi, Menachem Hanani, Joschen Roeper, Joshue A Goldberg.
Science Advances, Mar 10;7(11) (2021)
2020
Reversal of diet-induced hepatic steatosis by peripheral CB1 receptor blockade in mice is p53/miRNA-22/SIRT1/PPARa dependent
Shahar Azar, Shiran Udi, Adi Drori, Rivka Hadar, Alina Nemerovski, Kiran V Vemuri, Maya Miller, Dana Sherill-Rofe, Yhara Arad, Devorah Gur-Wahnon, Xiaoling Li, Alexandros Makriyannis, Danny Ben-Zvi, Yuval Tabach, Iddo Z Ben-Dov , Joseph Tam.
Molecular Metabolism. Sep 26(42) (2020)
Localized Antileptin Therapy Prevents Aortic Root Dilatation and Preserves Left Ventricular Systolic Function in a Murine Model of Marfan Syndrome
Sudeshna Fisch, Noa Bachner-Hinenzon, Offir Ertracht, Liang Guo, Yhara Arad, Danny Ben-Zvi, Ronglih Liao and Jacob Schneiderman.
Journal the American Heart Association. May 18;9(10):e014761. (2020)
2019
Intestine-Specific Overexpression of LDLR Enhances Cholesterol Excretion and Induces Metabolic Changes in Male Mice
Meoli L, Ben-Zvi D, Panciotti C, Kvas S, Pizarro P, Munoz R, Stylopoulos N.
Endocrinology, en.2018-00098, (2019)
2018
Cardiac leptin overexpression in the context of acute MI and reperfusion potentiates myocardial remodeling and left ventricular dysfunction
Kain D, Simon A, Greenberg A, Ben-Zvi D, Gilburd B, Schneiderman J.
PLoS ONE, Oct 12;13(10):e0203902. doi: 10.1371/journal.pone.0203902. (2018)
Time-Dependent Molecular Responses Differ between Gastric Bypass and Dieting but Are Conserved Across Species
Ben-Zvi D#, Meoli L, Abidi WM, Nestoridi E, Panciotti C, Castillo E, Pizzaro P, Shirley E, Gourash WF, Thompson CC, Munoz R, Clish CB, Anafi RC, Courcoulas AP, Stylopoulos N#.
Cell Metabolism, Aug 7;28(2):310-323.e6 (2018)
... and featured in Science
Sleeve gastrectomy improves glycemia independent of weight loss by restoring hepatic insulin sensitivity
Abu-Gazala S*, Horwitz E*, Ben-Haroush Schyr R, Bardugo A, Israeli H, Hija A, Schug J, Shin S, Dor Y, Kaestner KH# and Ben-Zvi D#.
Diabetes, Jun; 67(6): 1079-1085 (2018)
... and featured in F1000
ADMP controls the size of Spemann's Organizer through a network of self-regulating expansion-restriction signals
Leibovitz A*, Kot-Leibowitz H*, Ben-Zvi D, Fainsod A.
BMC Biology. Jan 22; 16:13 (2018)
2012-2016
Local application of leptin antagonist attenuates Angiotensin II-induced ascending aortic aneurysm
Ben-Zvi D, Savion N, Kolodgie F, Simon A, Fisch S, Schäfer K, Bachner-Hinenzon N, Cao X, Gertler A, Solomon G, Kachel ET, Raanani E, Lavi Y, Kotev Emeth S, Virmani R, Schoen F, Schneiderman J.
Journal the American Heart Association. May 3;5(5). pii: e003474. (2016)
Angptl4 links adipose tissue triglyceride metabolism with alpha-cell proliferation
Ben-Zvi D, Brannadon O, Hadley S, Peterson Q, Blum B, Melton DA.
PNAS. Dec 15, ;112(50):15498:503 (2015)
Modeling human nutrition using embryonic stem cells
Ben-Zvi D, Melton DA.
Cell. Mar 26;161(1):12-7 (2015)
Scaling Morphogen Gradients During Tissue Growth by a Cell Division Rule
Averbukh I*, Ben-Zvi D*, Mishra S*, Barkai N.
Development. June;141(10): (2014)
Scaling of Dorsal-Ventral Patterning in the Xenopus leavis Embryo
Ben-Zvi D, Fainsod A, Shilo BZ, Barkai N.
Bioessays. Feb;36(2):151-6 (2014)
Creating Gradients by Morphogen Shuttling.
Shilo BZ, Haskel-Ittah M, Ben-Zvi D, Schejter ED, Barkai N.
Trends in Genetics. Jan 28 (2013)
2008-2012
Glucose Metabolism: Key Endogenous Regulator of beta-cell Replication and Survival.
Dadon D, Tornovsky-Babaey S, Furth-Lavi J, Ben-Zvi D, Ziv O, Schyr-Ben-Haroush R, Stolovich-Rain M, Hija A, Porat S, Granot Z, Weinberg-Corem N, Dor Y, Glaser B.
Diabetes Obesity and Metabolism. Oct;14 Suppl 3:101-8 (2012)
Self-regulation of the head-inducing properties of the Spemann organizer
Inui M, Montagner M, Ben-Zvi D, Martello G, Soligo S, Manfrin A, Aragona M, Enzo E, Zacchigna L, Zanconato F, Azzolin L, Dupont S, Cordenonsi M, Piccolo S.
PNAS. Sep 18 109(38):15354-9 (2012)
Self-organized Shuttling: Generating Sharp Dorsoventral Polarity in the Early Drosophila Embryo
Haskel-Ittah M, Ben-Zvi D, Branski-Arieli M, Schejter ED, Shilo BZ, Barkai N.
Cell. Aug 31;150(5):1016-28 (2012)
Scaling of Mophogen Gradients
Ben-Zvi D, Shilo BZ, Barkai N.
Current opinion in Genetics and Development. Dec; 21(6):704-10 (2011)
Expansion-Repression Mechanism for Scaling the Dpp Activation Gradient in the Drosophila Wing Imaginal Disc
Ben-Zvi D, Pyrowolakis G, Barkai N, Shilo BZ.
Current Biology. Aug 23 21(16):1391-6 (2011)
Scaling of Morphogen Gradients by an Expansion-Repression Integral Feedback Control
Ben-Zvi D, Barkai N.
PNAS. Apr 13 107(15):6924-9 (2010)
"Big Frog, Small Frog": Maintaining Proportions in Embryonic Development
Ben-Zvi D, Barkai N.
FEBS Journal. Mar;276(5):1196-207 (2009)
Scaling of the BMP Activation Gradient in Xenopus Embryos
Ben-Zvi D, Shilo BZ, Fainsod A*,Barkai N*.
Nature. Jun. 26: 453(1799):1205-11 (2008)