top of page
Systems Biology of Endocrinology and Metabolism
Our lab is studies fundamental questions in endocrinology, metabolism, and metabolic diseases. How does the brain sense body composition? Why does the pancreas fail to secrete sufficient amounts of insulin in gestational and type 2 diabetes? How does it know to secrete just the right amount normally? What controls Ghrelin secretion? How much glucose do our liver and kidneys produce during exercise? To answer these questions we collaborate closely with physicians, use mouse models, tissue biopsies, and organoids, and develop computational and mathematical tools to crystalize our ideas.
Our ultimate goal is to gain a basic understanding of normal physiological processes and apply them to disease states.
bottom of page